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Article

Polygenic sex determination in vertebrates - is there any such thing?

Trends in genetics : TIG - 1 Apr 2023

Schartl Manfred, Georges Arthur, Marshall Graves Jennifer A

Abstract excerpt

Genetic sex determination (SD) in most vertebrates is controlled by a single master sex gene, which ensures a 1:1 sex ratio. However, more complex systems abound, and several have been ascribed to polygenic SD (PSD), in which many genes at different loci interact to produce the sexual phenotype. Here we examine claims for PSD in vertebrates, finding that most constitute transient states during sex chromosome...

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Identifiers

PMID: 36669949
DOI: 10.1016/j.tig.2022.12.002
PMCID: PMC10148267

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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