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Article

Subtotal Parathyroidectomy Successfully Controls Calcium Levels of Patients with Neonatal Severe Hyperparathyroidism Carrying a Novel CASR Mutation.

Hormone research in paediatrics - 1 Jan 2023

Wejaphikul Karn, Dejkhamron Prapai, Khorana Jiraporn, Watcharachan Kirati, Intachai Worrachet, Olsen Bjorn, Tongsima Sissades, Ketudat Cairns James R, Ngamphiw Chumpol, Kantaputra Piranit

Abstract excerpt

INTRODUCTION: Inactivating mutations of the calcium-sensing receptor (CASR) gene result in neonatal severe hyperparathyroidism (NSHPT). Total parathyroidectomy is an effective way to control life-threatening hypercalcemia in NSHPT but leads to permanent hypoparathyroidism. An alternative surgical option is subtotal parathyroidectomy. However, few cases were reported in the literature. Here, we report two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36626889
DOI: 10.1159/000528568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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