Article
Anti-amoebic activity of a series of benzofuran/benzothiophene derivatives against Acanthamoeba castellanii belonging to the T4 genotype.
Journal of applied microbiology - 23 Jan 2023
Akbar Noor, El-Gamal Mohammed I, Zaraei Seyed-Omar, Saeed Balsam Qubais, Khan Naveed Ahmed, Siddiqui Ruqaiyyah
Abstract excerpt
AIMS: To determine the anti-amoebic activity of benzofuran/benzothiophene-possessing compounds against Acanthamoeba castellanii of the T4 genotype. METHOD AND RESULTS: A series of benzofuran/benzothiophene-possessing compounds were tested for their anti-amoebic activities, in particular, to block encystation and excystation processes in amoebae. Cytotoxicity of the compounds were evaluated using lactate...
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