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Article

Horizontal transfer of the rfb cluster in Leptospira is a genetic determinant of serovar identity.

Life science alliance - 1 Feb 2023

Nieves Cecilia, Vincent Antony T, Zarantonelli Leticia, Picardeau Mathieu, Veyrier Frédéric J, Buschiazzo Alejandro

Abstract excerpt

Leptospira bacteria comprise numerous species, several of which cause serious disease to a broad range of hosts including humans. These spirochetes exhibit large intraspecific variation, resulting in complex tabulations of serogroups/serovars that crisscross the species classification. Serovar identity, linked to biological/clinical phenotypes, depends on the structure of surface-exposed LPS. Many LPS...

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PMID: 36622346
DOI: 10.26508/lsa.202201480
PMCID: PMC9736851

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