Article
Genome-wide association study of abdominal MRI-measured visceral fat: The multiethnic cohort adiposity phenotype study.
PloS one - 1 Jan 2023
Streicher Samantha A, Lim Unhee, Park S Lani, Li Yuqing, Sheng Xin, Hom Victor, Xia Lucy, Pooler Loreall, Shepherd John, Loo Lenora W M, Ernst Thomas, Buchthal Steven, Franke Adrian A, Tiirikainen Maarit, Wilkens Lynne R, Haiman Christopher A, Stram Daniel O, Cheng Iona, Le Marchand Loïc
Abstract excerpt
Few studies have explored the genetic underpinnings of intra-abdominal visceral fat deposition, which varies substantially by sex and race/ethnicity. Among 1,787 participants in the Multiethnic Cohort (MEC)-Adiposity Phenotype Study (MEC-APS), we conducted a genome-wide association study (GWAS) of the percent visceral adiposity tissue (VAT) area out of the overall abdominal area, averaged across L1-L5 (%VAT),...
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