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Article

Expanding repertoire of SARS-CoV-2 deletion mutations contributes to evolution of highly transmissible variants.

Scientific reports - 5 Jan 2023

Venkatakrishnan A J, Anand Praveen, Lenehan Patrick J, Ghosh Pritha, Suratekar Rohit, Silvert Eli, Pawlowski Colin, Siroha Abhishek, Chowdhury Dibyendu Roy, O'Horo John C, Yao Joseph D, Pritt Bobbi S, Norgan Andrew P, Hurt Ryan T, Badley Andrew D, Halamka John, Soundararajan Venky

Abstract excerpt

The emergence of highly transmissible SARS-CoV-2 variants and vaccine breakthrough infections globally mandated the characterization of the immuno-evasive features of SARS-CoV-2. Here, we systematically analyzed 2.13 million SARS-CoV-2 genomes from 188 countries/territories (up to June 2021) and performed whole-genome viral sequencing from 102 COVID-19 patients, including 43 vaccine breakthrough infections. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36604461
DOI: 10.1038/s41598-022-26646-5
PMCID: PMC9815892

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