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Evolutionary analysis and functional characterization reveal the role of the insulin-like growth factor system in a diversified selection of chickens (Gallus gallus).

Poultry science - 1 Mar 2023

Guo Yulong, Zhang Ke, Geng Wanzhuo, Chen Botong, Wang Dandan, Wang Zhang, Tian Weihua, Li Hong, Zhang Yanhua, Jiang Ruirui, Li Zhuanjian, Tian Yadong, Kang Xiangtao, Liu Xiaojun

Abstract excerpt

The insulin-like growth factor (IGF) system plays an indispensable role in embryonic and postnatal development in mammals. However, the effects of the system on growth, carcass, and egg-laying traits, and diversified selection have not been systematically studied in chickens. In the present study, firstly the composition and gene structures of the chicken IGF system were investigated using phylogenetic tree and...

Topics

Animals
Insulin-Like Growth Factor I
Chickens
Phylogeny
Insulin-Like Growth Factor II
Polymorphism, Single Nucleotide
Carrier Proteins
Mammals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36587453
DOI: 10.1016/j.psj.2022.102411
PMCID: PMC9816805

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