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Development and validation of the prognostic model based on autophagy-associated genes in idiopathic pulmonary fibrosis

12 Dec 2022

Abstract excerpt

Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease. Many studies suggest that autophagy may be related to disease progression and prognosis in IPF. However, the mechanisms involved have not been fully elucidated. Methods We incorporated 232 autophagy-associated genes (AAGs) and two datasets, GSE28042 and GSE27957, from the GEO database. Univariate Cox analysis and...

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PMID: 36578501
DOI: 10.3389/fimmu.2022.1049361

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