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Article

Characterization of SARS-CoV-2 omicron variants from Iran and evaluation of the effect of mutations on the spike, nucleocapsid, ORF8, and ORF9b proteins function.

Journal of biomolecular structure & dynamics - 1 Jan 2023

Ahmadi Khadijeh, Shahbazi Behzad, Zakeri Abdul-Jabbar, Gouklani Hamed

Abstract excerpt

The SARS-CoV-2 'Omicron' strain, with 15 mutations in the receptor binding domain (RBD), was detected in South Africa and rapidly spread worldwide. SARS-CoV-2 ORF9b protein by binding to the TOM70 receptor and ORF8 protein by binding to MHC-I, IF3 receptors inhibit the host's immune response. In this study, genomics variations were evaluated for 96 samples isolated from Iran from March to July 2022 using the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36576175
DOI: 10.1080/07391102.2022.2162131

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