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Article

Gingival tissue samples from periodontitis patients demonstrate epithelial-mesenchymal transition phenotype.

Journal of periodontal research - 1 Apr 2023

Saliem Saif S, Bede Salwan Y, Abdulkareem Ali A, Abdullah Bashar H, Milward Michael R, Cooper Paul R

Abstract excerpt

OBJECTIVE: To determine the expression of key epithelial-mesenchymal transition (EMT) markers in gingival tissue samples collected from patients with periodontitis. BACKGROUND: Epithelial-mesenchymal transition is a process responsible for shifting epithelial-phenotype to mesenchymal-phenotype leading to loss of epithelial-barrier function. Thus, EMT could be involved as a pathogenic mechanism in periodontitis as...

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PMID: 36575609
DOI: 10.1111/jre.13086

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