Article
SMAD6 inhibits granulosa cell proliferation and follicle growth rate in carrier and noncarrier heifers of the Trio allele.
Reproduction (Cambridge, England) - 1 Mar 2023
Domingues Rafael R, Andrade Fabiana S, Paulo N Andrade Joao, Moghbeli Sadrollah M, Gomez-Leon Victor, Madureira Guilherme, Mello Marco R B, Kirkpatrick Brian W, Wiltbank Milo C
Abstract excerpt
In brief: Follicle selection is a key event in monovular species. In this manuscript, we demonstrate the role of SMAD6 in promoting decreased granulosa cell proliferation and follicle growth rate in carriers vs noncarriers of the Trio allele and after vs before follicle deviation. Abstract: Cattle are generally considered a monovular species; however, recently, a bovine high fecundity allele, termed the Trio...
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