Development of liquid culture media mimicking the conditions of sinuses and lungs in cystic fibrosis and health

Abstract excerpt

The respiratory tract is a compartmentalised and heterogenous environment. The nasopharynx and sinuses of the upper airways have distinct properties from the lungs and these differences may shape bacterial adaptation and evolution. Upper airway niches act as early colonisation sites for respiratory bacterial pathogens, including those, such as Pseudomonas aeruginosa , that can go on to establish chronic infection...

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