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Article

Respiratory infections in X-linked hyper-IgM syndrome with CD40LG mutation: a case series of seven children in China.

BMC pediatrics - 22 Nov 2022

Fan Huifeng, Huang Li, Yang Diyuan, Zhang Changhao, Zeng Qiang, Yin Genquan, Lu Gen, Shen Kunling

Abstract excerpt

BACKGROUND: X-linked hyper-immunoglobulin M (XHIGM), a primary immunodeficiency syndrome caused by mutations in the CD40 ligand gene(CD40LG), presents with recurrent respiratory infections in pediatric patients. We aimed to evaluate the spectrum of clinical features and respiratory pathogens in pediatric patients with XHIGM in China. METHODS: We retrospectively reviewed seven pediatric patients who were diagnosed...

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Identifiers

PMID: 36419145
DOI: 10.1186/s12887-022-03726-z
PMCID: PMC9682706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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