Article
Binding of human ACE2 and RBD of Omicron enhanced by unique interaction patterns among SARS-CoV-2 variants of concern.
Journal of computational chemistry - 5 Feb 2023
Kim Seonghan, Liu Yi, Ziarnik Matthew, Seo Sangjae, Cao Yiwei, Zhang X Frank, Im Wonpil
Abstract excerpt
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing COVID-19, has continued to mutate and spread worldwide despite global vaccination efforts. In particular, the Omicron variant, first identified in South Africa in late November 2021, has become the dominant strain worldwide. Compared to the original strain identified in Wuhan, Omicron features 50 genetic mutations, with 15 mutations...
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