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Article

Selection of Diagnostically Significant Regions of the SLC26A4 Gene Involved in Hearing Loss.

International journal of molecular sciences - 3 Nov 2022

Danilchenko Valeriia Yu, Zytsar Marina V, Maslova Ekaterina A, Posukh Olga L

Abstract excerpt

Screening pathogenic variants in the SLC26A4 gene is an important part of molecular genetic testing for hearing loss (HL) since they are one of the common causes of hereditary HL in many populations. However, a large size of the SLC26A4 gene (20 coding exons) predetermines the difficulties of its complete mutational analysis, especially in large samples of patients. In addition, the regional or ethno-specific...

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Identifiers

PMID: 36362242
DOI: 10.3390/ijms232113453
PMCID: PMC9655724

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