Article
Mutation of the nuclear pore complex component, aladin1, disrupts asymmetric cell division in Zea mays (maize).
G3 (Bethesda, Md.) - 14 Jul 2021
Best Norman B, Addo-Quaye Charles, Kim Bong-Suk, Weil Clifford F, Schulz Burkhard, Johal Guri, Dilkes Brian P
Abstract excerpt
The nuclear pore complex (NPC) regulates the movement of macromolecules between the nucleus and cytoplasm. Dysfunction of many components of the NPC results in human genetic diseases, including triple A syndrome (AAAS) as a result of mutations in ALADIN. Here, we report a nonsense mutation in the maize ortholog, aladin1 (ali1-1), at the orthologous amino acid residue of an AAAS allele from humans, alters plant...
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