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Connecting multiple microenvironment proteomes uncovers the biology in head and neck cancer

7 Nov 2022

Abstract excerpt

The poor prognosis of head and neck cancer (HNC) is associated with metastasis within the lymph nodes (LNs). Herein, the proteome of 140 multisite samples from a 59-HNC patient cohort, including primary and matched LN-negative or -positive tissues, saliva, and blood cells, reveals insights into the biology and potential metastasis biomarkers that may assist in clinical decision-making. Protein profiles are...

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PMID: 36344512
DOI: 10.1038/s41467-022-34407-1

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