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Article

Association of IGF1 polymorphisms with exotropia in a Pakistani cohort.

Molecular vision - 1 Jan 2022

Zehra Zainab, Khan Netasha, Nadeem Minhal, Siddiqui Sorath Noorani, von Bartheld Christopher S, Azam Maleeha, Qamar Raheel

Abstract excerpt

Purpose: Strabismus (STBMS) is a multifactorial ocular disorder in children that leads to misalignment of the eyes. Insulin-like growth factor 1 (IGF1) has been shown to be involved in the development of extraocular muscles and myopia; however, data are limited on the genetic associations of IGF1 with STBMS in Pakistan. Methods: Two hundred seventy-four STBMS cases and 272 unaffected controls were recruited, and...

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PMID: 36338665
PMCID: PMC9603902

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