Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ubiquitin specific protease 46 potentiates triple negative breast cancer development by stabilizing PGAM1‐mediated glycolysis

6 Nov 2022

Abstract excerpt

Triple-negative breast cancer (TNBC) is a malignancy with high metastasis rate and poor prognosis. Limited drugs are effective for the treatment of TNBC patients. Ubiquitin specific proteases (USPs) are important posttranscription modulators that promote protein stability by reducing the ubiquitination of the proteins. Aberrant expression of USPs is involved in the development of numerous cancers. However, it...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Cancer-related Molecular Pathways
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36335636
DOI: 10.1002/cbin.11937

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ubiquitin specific protease 46 potentiates triple negative breast cancer development by stabilizing PGAM1‐mediated glycolysisPMID 36335636Read ↗

USP11 promotes glycolysis by regulating HIF ‐1α stability in hepatocellular carcinomaSemantic proximity Read ↗

USP22 Contributes to Chemoresistance, Stemness, and EMT Phenotype of Triple-Negative Breast Cancer Cells by egulating the Warburg Effect via c-Myc Deubiquitination.Semantic proximity Read ↗

The expression of ubiquitin‐specific peptidase 8 and its prognostic role in patients with breast cancerSemantic proximity Read ↗

Role of Ubiquitin-Specific Peptidase 47 in Cancers and Other DiseasesSemantic proximity Read ↗

The emerging role of ubiquitin-specific protease 20 in tumorigenesis and cancer therapeuticsSemantic proximity Read ↗

Emerging potential of ubiquitin-specific proteases and ubiquitin-specific proteases inhibitors in breast cancer treatmentSemantic proximity Read ↗

Gene Signature and Prognostic Value of Ubiquitin-Specific Proteases Members in Hepatocellular Carcinoma and Explored the Immunological Role of USP36Semantic proximity Read ↗

Ubiquitin-specific protease 14 targets PFKL-mediated glycolysis to promote the proliferation and migration of oral squamous cell carcinomaSemantic proximity Read ↗

System-wide identification of novel de-ubiquitination targets for USP10 in gastric cancer metastasis through multi-omics screeningSemantic proximity Read ↗

The deubiquitinating enzyme USP1 modulates ERα and modulates breast cancer progressionSemantic proximity Read ↗

Ubiquitin‐specific peptidase 24 accelerates aerobic glycolysis and tumor progression in gastric carcinoma through stabilizing PLK1 to activate NOTCH1Semantic proximity Read ↗

The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stabilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.