Article
Real-Time Whole Genome Sequencing to Guide Patient-Tailored Therapy of Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 21 Mar 2023
Snell Luke B, Alcolea-Medina Adela, Charalampous Themoula, Alder Christopher, Williams Tom G S, Flaviani Flavia, Batra Rahul, Bakrania Prijay, Thangarajah Rajeni, Neil Stuart J D, van Nispen Tot Pannerden Claire, Botgros Alina, Aarons Emma, Douthwaite Samuel T, Edgeworth Jonathan D, Nebbia Gaia
Abstract excerpt
The management of coronavirus disease 2019 has become more complex due to the expansion of available therapies. The presence of severe acute respiratory syndrome coronavirus 2 variants and mutations further complicates treatment due to their differing susceptibilities to therapies. Here we outline the use of real-time whole genome sequencing to detect persistent infection, evaluate for mutations confering...
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