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Article

Phenotypic variability in LAMA3-associated amelogenesis imperfecta.

Oral diseases - 1 Nov 2023

Wang Shih-Kai, Zhang Hong, Wang Yin-Lin, Seymen Figen, Koruyucu Mine, Simmer James P, Hu Jan C-C

Abstract excerpt

OBJECTIVE: Amelogenesis imperfecta (AI) is defined as inherited enamel malformations. LAMA3 (laminin alpha-3) encodes a critical protein component of the basement membrane (laminin-332). Individuals carrying heterozygous LAMA3 mutations have previously been shown to have localized enamel defects. This study aimed to define clinical phenotypes and to discern the genetic etiology for four AI kindreds. MATERIALS AND...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36326426
DOI: 10.1111/odi.14425
PMCID: PMC10154430

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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