Article
Pilot study on CHCF1 genotype in a pig challenge model for enterotoxigenic Escherichia coli F4ab/ac associated post-weaning diarrhea.
BMC veterinary research - 1 Nov 2022
Rydal Martin Peter, Gambino Michela, Jørgensen Claus Bøttcher, Poulsen Louise Ladefoged, Brøndsted Lone, Nielsen Jens Peter
Abstract excerpt
Host genotype is important for enterotoxigenic E. coli (ETEC) susceptibility. We conducted two trials to evaluate the effect of CHCF1 genotype on incidence of ETEC diarrhea. In trial 1 (n = 15 pigs), pigs were inoculated with 108 CFU or 1010 CFU doses of an ETEC F4ac strain. In trial 2 (n = 33 pigs), pigs were inoculated with ETEC F4ab or F4ac. Across trials, all inoculated pigs that developed ETEC diarrhea were...
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