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Tubulovillous adenoma with high-grade dysplasia of the vulva harboring high tumor mutational burden and cancer-associated mutations: a case report.

Diagnostic pathology - 28 Oct 2022

Sato Hanako, Murakami Kosuke, Otani Tomoyuki, Matsumura Noriomi

Abstract excerpt

BACKGROUND: Vulvar cancer is a rare disease, accounting for approximately 5% of gynecological malignancies. Primary adenocarcinoma of intestinal-type of the vulva or its precancerous lesion is extremely rare, and details regarding its origin, evolution and related genetic mutations are unknown. Treatment options for this cancer have not been defined. CASE PRESENTATION: A 63-year-old Japanese woman came to the...

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Identifiers

PMID: 36307835
DOI: 10.1186/s13000-022-01268-7
PMCID: PMC9615159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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