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Article

Cervical Pleuropulmonary Blastoma-like Tumor Associated With DICER1 and TP53 Mutations.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jul 2023

Stolnicu Simona, Bartalis Rolland-Jozsef, Mihut Emilia, Szabo Bela, Da Cruz Paula Arnaud, Ye Qiqi, Parkash Vinita, Weigelt Britta, Soslow Robert A

Abstract excerpt

We describe a very unusual cervical tumor in a 12-yr-old patient with a clinical history indicative of DICER1 syndrome. Morphologic, immunohistochemical, and molecular genetic analysis together helped to diagnose this lesion as a cervical pleuropulmonary blastoma-like tumor, associated with TP53 and DICER1 mutations. The tumor displayed usual histologic features including mixtures of embryonal rhabdomyosarcoma,...

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Identifiers

PMID: 36302256
DOI: 10.1097/PGP.0000000000000927
PMCID: PMC10357386

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