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Article

Influence of UGT1A1 Genetic Variants on Free Bilirubin Levels in Japanese Newborns: A Preliminary Study.

International journal of environmental research and public health - 12 Oct 2022

Hanafusa Hiroaki, Abe Shinya, Ohyama Shohei, Kyono Yuki, Kido Takumi, Nakasone Ruka, Ashina Mariko, Tanimura Kenji, Nozu Kandai, Fujioka Kazumichi

Abstract excerpt

BACKGROUND: Free bilirubin (Bf) is a better marker than total serum bilirubin (TSB) for predicting bilirubin encephalopathy (BE). To date, two UGT1A1 genetic variants (rs4148323 and rs3064744) have been associated with neonatal hyperbilirubinemia; however, the direct association between UGT1A1 variants and Bf levels in newborns has not been elucidated. METHODS: We retrospectively analyzed the clinical data of 484...

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Identifiers

PMID: 36293671
DOI: 10.3390/ijerph192013090
PMCID: PMC9603041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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