Article
Leptospira enrichment culture followed by ONT metagenomic sequencing allows better detection of Leptospira presence and diversity in water and soil samples
26 Oct 2022
Abstract excerpt
BACKGROUND: Leptospirosis, a life-threatening disease in humans and animals, is one of the most widespread global zoonosis. Contaminated soil and water are the major transmission sources in humans and animals. Clusters of disease outbreaks are common during rainy seasons. METHODOLOGY/PRINCIPAL FINDINGS: In this study, to detect the presence of Leptospira, we applied PCR, direct metagenomic sequencing, and...
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