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Article

Th17 cells in primary Sjögren’s syndrome negatively correlate with increased Roseburia and Coprococcus

5 Oct 2022

Abstract excerpt

Background Dysbiosis of the gut microbiota is closely related to chronic systemic inflammation and autoimmunity, playing an essential role in the pathogenesis of primary Sjögren’s syndrome (pSS). Abnormalities in the proportions of blood T lymphocyte subtype, that is Th17/Treg, were detected in pSS patients. We aimed to determine the associations between gut microbiota and Th17/Treg in pSS. Method 98 pSS patients...

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PMID: 36275752
DOI: 10.3389/fimmu.2022.974648

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