Article
Connection between the Gut Microbiome, Systemic Inflammation, Gut Permeability and FOXP3 Expression in Patients with Primary Sjögren's Syndrome.
International journal of molecular sciences - 19 Nov 2020
Cano-Ortiz Antonio, Laborda-Illanes Aurora, Plaza-Andrades Isaac, Membrillo Del Pozo Alberto, Villarrubia Cuadrado Alberto, Rodríguez Calvo de Mora Marina, Leiva-Gea Isabel, Sanchez-Alcoholado Lidia, Queipo-Ortuño María Isabel
Abstract excerpt
The aims of this study were to explore intestinal microbial composition and functionality in primary Sjögren's syndrome (pSS) and to relate these findings to inflammation, permeability and the transcription factor Forkhead box protein P3 (FOXP3) gene expression in peripheral blood. The study included 19 pSS patients and 19 healthy controls matched for age, sex, and body mass index. Fecal bacterial DNA was...
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