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Article

Genetic diversity and evolutionary convergence of cryptic SARS- CoV-2 lineages detected via wastewater sequencing.

PLoS pathogens - 1 Oct 2022

Gregory Devon A, Trujillo Monica, Rushford Clayton, Flury Anna, Kannoly Sherin, San Kaung Myat, Lyfoung Dustin T, Wiseman Roger W, Bromert Karen, Zhou Ming-Yi, Kesler Ellen, Bivens Nathan J, Hoskins Jay, Lin Chung-Ho, O'Connor David H, Wieberg Chris, Wenzel Jeff, Kantor Rose S, Dennehy John J, Johnson Marc C

Abstract excerpt

Wastewater-based epidemiology (WBE) is an effective way of tracking the appearance and spread of SARS-COV-2 lineages through communities. Beginning in early 2021, we implemented a targeted approach to amplify and sequence the receptor binding domain (RBD) of SARS-COV-2 to characterize viral lineages present in sewersheds. Over the course of 2021, we reproducibly detected multiple SARS-COV-2 RBD lineages that have...

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Identifiers

PMID: 36240259
DOI: 10.1371/journal.ppat.1010636
PMCID: PMC9604950

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