Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A New HIV-1 K28E32-Reverse Transcriptase Variant Associated with the Rapid Expansion of CRF07_BC among Men Who Have Sex with Men.

Microbiology spectrum - 26 Oct 2022

Han Jingwan, Zhou Yan-Heng, Ma Yingying, Zhu Guoxin, Zhang Dong, Zhu Bo, Cheng Tong, Wang Lanfeng, Wang Jian-Hua, Li Lin, Zhang Chiyu

Abstract excerpt

HIV-1 CRF07_BC originated among injection drug users (IDUs) in China. After diffusing into men who have sex with men (MSM), CRF07_BC has shown a rapid expansion in this group; however, the mechanism remains unclear. Here, we identified a new K28E32 variant of CRF07_BC that was characterized by five specific mutations (E28K, K32E, E248V, K249Q, and T338S) in reverse transcriptase. This variant was mainly prevalent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Homosexuality, Male

Share to Phylogeny

Share to RNA-Directed DNA Polymerase

Share to Sexual and Gender Minorities

Source

Open in PubMed Open full text

Identifiers

PMID: 36214682
DOI: 10.1128/spectrum.02545-22
PMCID: PMC9604004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A New HIV-1 K28E32-Reverse Transcriptase Variant Associated with the Rapid Expansion of CRF07_BC among Men Who Have Sex with Men.PMID 36214682Read ↗

Genomic Characteristics of the New HIV-1 CRF07_BC K28E32 Variant.Semantic proximity Read ↗

Enhanced Transmissibility and Decreased Virulence of HIV-1 CRF07_BC May Explain Its Rapid Expansion in China.Semantic proximity Read ↗

HIV-1 CRF07_BC transmission dynamics in China: two decades of national molecular surveillanceSemantic proximity Read ↗

Identification of Two Novel HIV-1 Unique Recombinant Forms Among Men Who Have Sex with Men in Northern China.Semantic proximity Read ↗

Spatiotemporal Patterns of CRF07_BC in China: A Population-Based Study of the HIV Strain With the Highest Infection RatesSemantic proximity Read ↗

Identification of Three Novel HIV-1 Second-Generation Recombinant Forms (CRF01_AE/CRF07_BC) Among Men Who Have Sex with Men in Baoding, Hebei, China.Semantic proximity Read ↗

Surging HIV-1 CRF07_BC epidemic among recently infected men who have sex with men in Fujian, China.Semantic proximity Read ↗

Genomic Characterization of a Novel HIV-1 Second-Generation Recombinant (CRF01_AE/CRF07_BC) Identified from a Men Who Have Sex with Men (MSM) Patient in Hebei, China.Semantic proximity Read ↗

Identification of a Novel HIV Type 1 Recombinant Form (CRF01_AE/CRF07_BC) in Men Who Have Sex with Men in Zhejiang, China.Semantic proximity Read ↗

Identification of a Novel CRF01_AE/CRF07_BC Recombinant Form in Men Who Have Sex with Men in Sichuan, China.Semantic proximity Read ↗

Genetic Characterization of a Novel HIV-1 Second-Generation Recombinant Form (CRF01_AE/CRF07_BC) Identified in Yan'an City, China.Semantic proximity Read ↗

Near Full-Length Genomic Characterization of a Novel HIV Type 1 CRF07_ BC/01_AE Recombinant in Men Who Have Sex with Men from Sichuan, ChinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.