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Article

A gene-environment cascade theoretical framework of developmental psychopathology.

Journal of psychopathology and clinical science - 1 Apr 2023

Elam Kit K, Lemery-Chalfant Kathryn, Chassin Laurie

Abstract excerpt

Previous theories have emphasized genetic effects "inside the skin" via endophenotypes within the broader developmental psychopathology theory. Expanding on the mechanisms of gene-environment correlation, we propose a new integrative framework emphasizing how genetic effects "outside the skin" (Reiss & Leve, 2007) accumulate due to individual variation in social information processing in negative environments and...

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Identifiers

PMID: 36201798
DOI: 10.1037/abn0000546
PMCID: PMC10076453

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