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Signaling pathways and targeted therapies in lung squamous cell carcinoma: mechanisms and clinical trials

5 Oct 2022

Abstract excerpt

Lung cancer is the leading cause of cancer-related death across the world. Unlike lung adenocarcinoma, patients with lung squamous cell carcinoma (LSCC) have not benefitted from targeted therapies. Although immunotherapy has significantly improved cancer patients' outcomes, the relatively low response rate and severe adverse events hinder the clinical application of this promising treatment in LSCC. Therefore, it...

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PMID: 36198685
DOI: 10.1038/s41392-022-01200-x

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