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[Bone marrow failure and TP53 activating mutations].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2022

Ito Etsuro

Abstract excerpt

Inherited bone marrow failure syndrome (IBMFS) is a heterogeneous group of genetic disorders characterized by bone marrow failure, congenital anomalies, and an increased risk of malignancy. The p53 tumor suppressor protein is a transcription factor activated in response to various cellular stresses and induces genes involved in apoptosis, cell cycle arrest, and DNA repair. Several lines of evidence suggest that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36198537
DOI: 10.11406/rinketsu.63.1115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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