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Article

Dimensions of childhood adversity differentially affect biological aging in major depression

4 Oct 2022

Abstract excerpt

Adverse childhood experiences have been consistently linked with physical and mental health disorders in adulthood that may be mediated, in part, via the effects of such exposures on biological aging. Using recently developed "epigenetic clocks", which provide an estimate of biological age, several studies have demonstrated a link between the cumulative exposure to childhood adversities and accelerated epigenetic...

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PMID: 36195591
DOI: 10.1038/s41398-022-02198-0

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