Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A role of gut-microbiota-brain axis via subdiaphragmatic vagus nerve in depression-like phenotypes in Chrna7 knock-out mice.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2023

Yang Yong, Eguchi Akifumi, Wan Xiayun, Chang Lijia, Wang Xingming, Qu Youge, Mori Chisato, Hashimoto Kenji

Abstract excerpt

The α7 subtype of the nicotinic acetylcholine receptor (α7 nAChR: coded by Chrna7) is known to regulate the cholinergic ascending anti-inflammatory pathway. We previously reported that Chrna7 knock-out (KO) mice show depression-like behaviors through abnormal composition of gut microbiota and systemic inflammation. Given the role of subdiaphragmatic vagus nerve in gut-microbiota-brain axis, we investigated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha7 Nicotinic Acetylcholine Receptor
Share to Anti-Inflammatory Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depression

Share to Lactobacillus

Share to Microbiota

Share to Receptors, Nicotinic

Share to Vagus Nerve

Source

Identifiers

PMID: 36191806
DOI: 10.1016/j.pnpbp.2022.110652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A role of gut-microbiota-brain axis via subdiaphragmatic vagus nerve in depression-like phenotypes in Chrna7 knock-out mice.PMID 36191806Read ↗

A role of the subdiaphragmatic vagus nerve in depression-like phenotypes in mice after fecal microbiota transplantation from Chrna7 knock-out mice with depression-like phenotypes.Semantic proximity Read ↗

A key role of the subdiaphragmatic vagus nerve in the depression-like phenotype and abnormal composition of gut microbiota in mice after lipopolysaccharide administration.Semantic proximity Read ↗

Unveiling the Synapses: Gut Microbiota and Neurodegenerative Disorders Through the Gut–Brain AxisSemantic proximity Read ↗

Depression-like phenotypes in mice with hepatic ischemia/reperfusion injury: A role of gut-microbiota-liver-brain axis via vagus nerve.Semantic proximity Read ↗

Epigenetics in depression and gut-brain axis: A molecular crosstalkSemantic proximity Read ↗

Vagal Sensing of Altered Gut Microbiota Links to Externalizing BehaviorsSemantic proximity Read ↗

Effects of spleen nerve denervation on depression-like phenotype, systemic inflammation, and abnormal composition of gut microbiota in mice after administration of lipopolysaccharide: A role of brain-spleen axis.Semantic proximity Read ↗

Gut–Brain Axis: Role of Gut Microbiota on Neurological Disorders and How Probiotics/Prebiotics Beneficially Modulate Microbial and Immune Pathways to Improve Brain FunctionsSemantic proximity Read ↗

Biogenic Amines: Signals Between Commensal Microbiota and Gut PhysiologySemantic proximity Read ↗

Multi-species probiotic supplement enhances vagal nerve function – results of a randomized controlled trial in patients with depression and healthy controlsSemantic proximity Read ↗

The Contribution of Gut Microbiota–Brain Axis in the Development of Brain DisordersSemantic proximity Read ↗

The gut microbiome and depression: a reviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.