The population genomic legacy of the second plague pandemic

Abstract excerpt

Human populations have been shaped by catastrophes that may have left long-lasting signatures in their genomes. One notable example is the second plague pandemic that entered Europe in ca. 1,347 CE and repeatedly returned for over 300 years, with typical village and town mortality estimated at 10%–40%. 1 It is assumed that this high mortality affected the gene pools of these populations. First, local population...

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