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Systemic antibody responses against human microbiota flagellins are overrepresented in chronic fatigue syndrome patients

23 Sept 2022

Abstract excerpt

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease with an unclear etiology and pathogenesis. Both an involvement of the immune system and gut microbiota dysbiosis have been implicated in its pathophysiology. However, potential interactions between adaptive immune responses and the microbiota in ME/CFS have been incompletely characterized. Here, we profiled antibody responses of...

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PMID: 36149952
DOI: 10.1126/sciadv.abq2422

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