Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigation of Klotho G395A and C1818T Polymorphisms and Their Association with Serum Glucose Level and Risk of Type 2 Diabetes Mellitus.

Genes - 26 Aug 2022

Aziz Muhammad Sadiq, Aamir Aziz-Ul-Hasan, Khan Ajab, Khan Zahid, Shah Syed Qaiser, Safi Sher Zaman, Batumalaie Kalaivani, Alobaid Hussah M, Ali Abid, Imran Muhammad

Abstract excerpt

Objective: The objective was to study the association of Klotho gene G395A and C1818T single nucleotide polymorphisms with glycemia, serum, glycosylated hemoglobin (HbA1c) level and the risk of type 2 diabetes mellitus (T2DM) in the Pashtun population of Pakistan. Methods: In this study, 195 normal individuals and 217 T2DM patients were enrolled. All subjects were divided into three groups, namely overall...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronidase

Share to Glycated Hemoglobin

Share to Hydrolases

Share to Klotho Proteins

Share to Lipids

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 36140700
DOI: 10.3390/genes13091532
PMCID: PMC9498819

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of Klotho G395A and C1818T Polymorphisms and Their Association with Serum Glucose Level and Risk of Type 2 Diabetes Mellitus.PMID 36140700Read ↗

KLOTHO gene polymorphisms G-395A and C1818T are associated with lipid and glucose metabolism, bone mineral density and systolic blood pressure in Japanese healthy subjects.Semantic proximity Read ↗

Relationship between polymorphisms G395A in promoter and C1818T in exon 4 of the KLOTHO gene with glucose metabolism and cardiovascular risk factors in Korean women.Semantic proximity Read ↗

The Klotho gene G-395A polymorphism and metabolic syndrome in very elderly people.Semantic proximity Read ↗

G-395A polymorphism in the promoter region of the KLOTHO gene and hypertension among elderly (90 years and older) Chinese individuals.Semantic proximity Read ↗

Association of the polymorphisms 292 C>T and 1304 G>A in the SLC38A4 gene with hyperglycaemia.Semantic proximity Read ↗

Association of SNP rs9939609 in FTO gene with metabolic syndrome in type 2 diabetic subjects, rectruited from a tertiary care unit of Karachi, PakistanSemantic proximity Read ↗

Common variant within the FTO gene, rs9939609, obesity and type 2 diabetes in population of Karachi, Pakistan.Semantic proximity Read ↗

Association of exonic variants of Klotho with metabolic syndrome in Asian Indians.Semantic proximity Read ↗

Circulating C5L2 gene polymorphism is associated with type 2 diabetes mellitus in Saudi population.Semantic proximity Read ↗

Association study of the single-nucleotide polymorphisms -3971G/A and +276G/T in the adiponectin gene with type 2 diabetes in a North Indian Punjabi population.Semantic proximity Read ↗

KLOTHO gene polymorphisms G-395A and C1818T are associated with low-density lipoprotein cholesterol and uric acid in Japanese hemodialysis patients.Semantic proximity Read ↗

Association between OX40L polymorphism and type 2 diabetes mellitus in Iranians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.