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Article

Establishment of two iPSC lines from healthy donor with heterozygous mutation in the SLC26A4 gene.

Stem cell research - 1 Oct 2022

Li SiJun, He Chufeng, Feng Qi, Bai YiJiang, Liu Xianlin, Ling Jie, Mei Lingyun, Wu XueWen, Feng Yong, Song Jian

Abstract excerpt

The human induced pluripotent stem cell (iPSC) lines, CSUXHEi001-A and CSUXHEi002-A, were generated from peripheral blood mononuclear cells (PBMCs). The donors were couple and each of them has a heterozygous mutation in the SLC26A4 gene. It manifests in their children as Enlarged vestibular aqueduct (EVA). The use of iPSC will allow describing the early stages of hearing loss, which is undoubtedly relevant for...

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Identifiers

PMID: 36126472
DOI: 10.1016/j.scr.2022.102916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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