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Article

A three-pronged analysis confirms the association of the serotoninergic system with attention deficit hyperactivity disorder.

World journal of pediatrics : WJP - 1 Dec 2022

Chatterjee Mahasweta, Saha Sharmistha, Sinha Swagata, Mukhopadhyay Kanchan

Abstract excerpt

BACKGROUND: The serotonin transporter (SERT), encoded by the solute carrier family 6 number 4 (SLC6A4) gene, controls serotonin (5-HT) availability and is essential for the regulation of behavioral traits. Two SLC6A4 genetic variants, 5-HTTLPR and STin2, were widely investigated in patients with various neurobehavioral disorders, including attention deficit hyperactivity disorder (ADHD). METHODS: We analyzed the...

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PMID: 36123504
DOI: 10.1007/s12519-022-00614-5

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