Article
The maternal prenatal and offspring early-life gut microbiome of childhood asthma phenotypes.
Allergy - 1 Feb 2023
Lee-Sarwar Kathleen A, Chen Yih-Chieh, Chen Yuan Yao, Kozyrskyj Anita L, Mandhane Piush J, Turvey Stuart E, Subbarao Padmaja, Bisgaard Hans, Stokholm Jakob, Chawes Bo, Sørensen Søren J, Kelly Rachel S, Lasky-Su Jessica, Zeiger Robert S, O'Connor George T, Sandel Megan T, Bacharier Leonard B, Beigelman Avraham, Carey Vincent J, Harshfield Benjamin J, Laranjo Nancy, Gold Diane R, Weiss Scott T, Litonjua Augusto A
Abstract excerpt
BACKGROUND: The infant fecal microbiome is known to impact subsequent asthma risk, but the environmental exposures impacting this association, the role of the maternal microbiome, and how the microbiome impacts different childhood asthma phenotypes are unknown. METHODS: Our objective was to identify associations between features of the prenatal and early-life fecal microbiomes and child asthma phenotypes. We...
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