Pre-pubertal smoke exposure of fathers and increased risk of offspring asthma: a possible transgenerational effect

Abstract excerpt

Asthma is a major non-communicable disease in children [1]. Pre- and post-natal exposure to tobacco smoke are major risk factors for childhood asthma [1, 2]. While there is evidence that mothers' intrauterine exposure to second-hand smoke is associated with asthma in the offspring [3, 4], there is also increasing concern that fathers who start smoking before completing puberty may elevate the risk of asthma in...

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