Article
The Impact of SARS-CoV-2 Variants on the Clinical Phenotype and Severity of Multisystem Inflammatory Syndrome in Children in South Africa.
The Pediatric infectious disease journal - 1 Dec 2022
Abraham Deepthi Raju, Butters Claire, Abdulbari Yunis Nurea, Lishman Juanita, Scott Christiaan, van der Zalm Marieke M, Zühlke Liesl, Rabie Helena, Webb Kate
Abstract excerpt
The effects of SARS-CoV-2 variants on disease phenotype and severity of multisystem inflammatory syndrome in children (MIS-C) are unknown. We compared the clinical phenotype of MIS-C in 129 South African children across four distinct (Ancestral type, Beta, Delta, and Omicron) variant-driven waves and found that MIS-C remains a severe disease with a stable clinical presentation, regardless of variant.
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