Article
Generative Moment Matching Networks for Genotype Simulation.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jul 2022
Perera Maria, Montserrat Daniel Mas, Barrabes Miriam, Geleta Margarita, Giro-I-Nieto Xavier, Ioannidis Alexander G
Abstract excerpt
The generation of synthetic genomic sequences using neural networks has potential to ameliorate privacy and data sharing concerns and to mitigate potential bias within datasets due to under-representation of some population groups. However, there is not a consensus on which architectures, training procedures, and evaluation metrics should be used when simulating single nucleotide polymorphism (SNP) sequences with...
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