Article
Synthetic observations from deep generative models and binary omics data with limited sample size.
Briefings in bioinformatics - 20 Jul 2021
Nußberger Jens, Boesel Frederic, Lenz Stefan, Binder Harald, Hess Moritz
Abstract excerpt
Deep generative models can be trained to represent the joint distribution of data, such as measurements of single nucleotide polymorphisms (SNPs) from several individuals. Subsequently, synthetic observations are obtained by drawing from this distribution. This has been shown to be useful for several tasks, such as removal of noise, imputation, for better understanding underlying patterns, or even exchanging data...
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