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Article

The potential of mecciRNA in hepatic stellate cell to regulate progression of nonalcoholic hepatitis

4 Sept 2022

Abstract excerpt

BACKGROUND: Nonalcoholic steatohepatitis (NASH) occupies a substantial proportion of chronic liver disease worldwide, of which pathogenesis needs further research. Recent studies have demonstrated the significant roles of circular RNAs (circRNAs) in NASH, while the function of a novel type of circRNAs, namely mitochondria-encoded circRNAs (mecciRNAs), remains elusive. Therefore, we aimed to investigate their...

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PMID: 36058953
DOI: 10.1186/s12967-022-03595-1

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