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Article

Circular RNA expression profiles and features in NAFLD mice: a study using RNA-seq data

1 Dec 2020

Abstract excerpt

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is primarily characterized by the hepatic cholesterol accumulation. Circular RNA (circRNA), one of noncoding RNA, involves in many liver diseases progression. However, no recent studies on circRNA expression profiles in NAFLD have been reported previously. METHODS: A NAFLD mouse model was constructed by providing high-fat diet (HFD) for 32 weeks. The circRNAs...

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PMID: 33308253
DOI: 10.1186/s12967-020-02637-w

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