Article
Structural variants and tandem repeats in the founder individuals of four F2 pig crosses and implications to F2 GWAS results.
BMC genomics - 3 Sept 2022
Blaj Iulia, Tetens Jens, Bennewitz Jörn, Thaller Georg, Falker-Gieske Clemens
Abstract excerpt
BACKGROUND: Structural variants and tandem repeats are relevant sources of genomic variation that are not routinely analyzed in genome wide association studies mainly due to challenging identification and genotyping. Here, we profiled these variants via state-of-the-art strategies in the founder animals of four F2 pig crosses using whole-genome sequence data (20x coverage). The variants were compared at a founder...
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