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HMOX1 promotes lung adenocarcinoma metastasis by affecting macrophages and mitochondrion complexes

12 Aug 2022

Abstract excerpt

Background: Metastasis is the leading cause of lung adenocarcinoma (LUAD) patient death. However, the mechanism of metastasis is unclear. We performed bioinformatic analyses for HMOX1 (Heme oxygenase-1), aiming to explore its role in LUAD metastasis. Methods: Pan-cancer analysis was first used to identify the metastasis-associated role of HMOX1 in LUAD. HMOX1-related genomic alterations were then investigated....

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PMID: 36033490
DOI: 10.3389/fonc.2022.978006

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