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Using the canine microbiome to bridge translation of cancer immunotherapy from pre-clinical murine models to human clinical trials

12 Aug 2022

Abstract excerpt

The microbiome has clearly been established as a cutting-edge field in tumor immunology and immunotherapy. Growing evidence supports the role of the microbiome in immune surveillance, self-tolerance, and response to immune checkpoint inhibitors such as anti PD-L1 and CTLA-4 blockade (1-6). Moreover, recent studies including those using fecal microbial transplantation (FMT) have demonstrated that response to...

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PMID: 36032113
DOI: 10.3389/fimmu.2022.983344

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